Coalition for National Trauma Research

National Trauma Research Action Plan (NTRAP) - More than 400 trauma care investigators and stakeholders participating in the NTRAP project are performing a gap analysis to identify research priorities across the continuum of care, defining optimal metrics to assess long-term functional outcomes following hospital discharge, and identifying regulatory barriers and best practices for clinical trauma research. To date the project has resulted in 15 publications and 2 additional manuscripts are in process. An investigator toolkit addressing regulatory challenges to conducting trauma research is published on the Nattrauma.org website, and a number of investigators are requesting data from the project in order to conduct secondary analyses.

PROPOLIS - The PROpOLIS (Plasma Resuscitation withOut Lung Injury) study examines the use of INTERCEPT-treated pathogen-reduced plasma (IPRP) in the resuscitation of burned patients. IPRP is an FDA-approved blood component that has undergone treatment to reduce the risk of transfusion-transmitted infection. As the coordinating center for the multi-institutional study, CNTR is responsible for end-to-end study management across five clinical sites and two laboratories involving all policy and procedure, training, and human subject protection activities. This three-year study, funded by the Defense Medical Research and Development Program, is now enrolling patients.

PCORI VTE This project implements a nurse VTE education program at 9 trauma centers in addition to the lead site. To date, 1,104 nurses have completed the training, data reports and the set-up of the real-time missed dose alerts are in process. In addition, nurse peer coaching has begun at all 9 sites. A Delphi Survey on Peri-Procedural VTE Prophylaxis is in process, and two publications have been drafted for submission.

Mimic

Lumify

Humacyte

PCORI Engagement

VTE Conference

Kericure

CSL Behring

Burn Sepsis